Early-stage venture · Los Angeles, California

Early-stage capital for breakthrough deeptech.

EGB Capital invests in early-stage companies commercializing breakthrough science across engineered biology, novel chemistries, and other defensible deeptech sectors.

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Early-stage investment across biology, therapeutics and deeptech

EGB Capital is an early-stage venture capital firm based in Los Angeles. We invest in transformative, technically defensible companies developing breakthrough scientific and engineering innovation.

We partner with deeply technical, mission-driven founders at the earliest stages to help shape commercialization, partnership, and patient impact to build toward durable long-term value.

What we invest in

We primarily invest at pre-seed and seed, with selective participation in Series A, across the United States and Europe.

Therapeutic plaforms

Synthetic biology

Biomanufacturing

Cell and gene therapy infrastructure

Novel chemistries

Advanced materials

Computational biology

Enabling deeptech platforms

Our thesis

We believe some of the most important companies of the next decade will come from overlooked technical breakthroughs rather than crowded hype cycles.

We are especially drawn to companies with strong technical differentiation, defensible intellectual property, clear unmet market need, and the potential to unlock entirely new capabilities across large markets.

  1. 01Critical unsolved problems
  2. 02Overlooked but important parts of the value chain
  3. 03Platform and enabling technologies
  4. 04Strong technical moats
  5. 05Deeply technical, mission-driven founders
  6. 06Commercial pathways grounded in real-world value

Portfolio

We invest in companies pursuing technically ambitious work with the potential to create real commercial and industrial impact.

CellFE

Microfluidics-based platform for cell therapy manufacturing.

Syntax Bio

Synthetic biology platform facilitating pre-programmed sequential CRISPR activations for cell differentiation.

Izote Biosciences

Bioproduction platform utilizing anaerobic respiration.

DesiCorp

Technology for freeze-drying human red blood cells for transport and long-term storage.

SoFab

Low-cost, high-performance electron transport layers.

Kebotix

Materials discovery and chemical optimization.

MiLaboratories

Computational biology platform for next-generation therapeutic development.

Circe

Carbon-negative manufacturing of essential fats.

Sironix Renewables

Bio-based, non-carcinogenic anionic surfactants.

Fork & Good

Cellular engineering platform for cultivated pork and beef cells without growth factors.

Dinya DNA

Synthetic biology platform producing ultra-long DNA sequences with high fidelity and low cost.

Enrich Biosystems

3D-printed hydrogel microwells for high-throughput co-culture cell screening.

Swan Genomics

Low-cost genomic sequencing using plasmonic nanoantennae and DNA origami.

RiboForge

Technology for deriving 3D structures of mRNA and pre-mRNA.

Biotia

Pathogen sequencing platform for biosecurity and diagnostics.

Extellis

Metamaterial technology designed to reduce the cost of mSAR satellite imagery.

Sift Biosciences

Molecular mimics designed to turn cold tumors into immune targets.

Heritable Agriculture

Making plants programmable.

Team

Douglas Munsey

Douglas Munsey

Founder & Managing Partner

LinkedIn

Douglas Munsey is an entrepreneur, investor, and healthcare operator focused on identifying compelling early-stage deeptech opportunities and supporting portfolio companies as they grow.

Prior to founding EGB Capital, Douglas helped launch the Olympus Innovation Fund at Touchdown Ventures. He began his investment career as an analyst at Morgan Stanley covering the medical technology sector.

Earlier in his career, Douglas was one of the first employees at medical device manufacturer Ki Mobility, where he held a range of operating roles spanning purchasing, logistics, and data analysis. He helped the company scale to more than $60 million in revenue and supported its sale to ETAC.

Douglas was also a co-founder of Syntax Bio, a synthetic biology platform focused on precision cell differentiation. The company has raised capital from prominent biotech investors and secured a development partnership with Astellas Pharmaceuticals.

As an angel investor, Douglas has made more than a dozen investments in early-stage companies.

He holds a B.B.A. from the University of Wisconsin–Madison, and both an M.P.H. and M.B.A. from the University of California, Berkeley.

Luke Riggan

Luke Riggan

Scientific Advisor

LinkedIn

Luke Riggan is an immunologist and biotech founder.

He founded ImmunoVec, a gene and cell therapy spinout from UCLA, giving him first-hand experience taking a technology out of an academic lab and building a company around it.

At EGB Capital, Luke advises on scientific diligence across therapeutics, cell engineering, and enabling biology platforms, helping assess the technical foundations behind early-stage opportunities.

He holds a Ph.D. from the University of California, Los Angeles.

What founders say

“Doug gives useful and pointed strategic advice without being overbearing. He is particularly capable at translating technical capabilities into viable commercial approaches.”
Sam AtwoodCo-founder & CEO, Izote Biosciences
“Douglas has supported CellFE from the beginning and believed in us before anyone else. His advice and support have been instrumental in getting the company to where it is today.”
Alla Zamarayeva, PhDCo-founder & CEO, CellFE
“Doug has always had Syntax’s best interests in mind. Through thick and thin, he has been there when very few investors, or none, have been there for the company.”
Ryan Clarke, PhDCo-founder & CEO, Syntax Bio

Get in touch

Whether you’re a founder building in deeptech or an investor interested in learning more about EGB Capital, we’d be glad to hear from you.

contact

Los Angeles, California

EGB Capital